1. School of Medicine
  2. Research groups
  3. Imaging

Imaging

  • Group summary: World class imaging in rheumatic and musculoskeletal diseases.

What we do

Imaging is a major cross-cutting theme for all the research groups within LIRMM. We have been world-leading in developing the use of modern imaging, especially MRI and ultrasound, to study pathogenesis, stratification for intervention, outcome measurement and care pathway evolution across the rheumatic and musculoskeletal disorders. The group played a leading role in the development of the Outcome Measures in Rheumatology (OMERACT) imaging tools development, and maintain strong involvement with OMERACT and with the EULAR Standing Committee on Musculoskeletal Imaging.

Disease areas we are currently working in: reumatoid arthritis (and pre-RA), ankylosing spondylitis, psoriatic arthritis, systemic lupus erythematosus, scleroderma, osteoarthritis, post-joint replacement (with metal suppression techniques), giant cell arteritis.

Anatomical regions studied: spine, knee, hip, hand and wrist, shoulder, foot and ankle, whole body techniques.

Anatomical structures studied: bone, synovium, cartilage, meniscus, tendon, enthesis, skin.

We use a broad range of MRI (including pre and post-contrast, DCE-MRI) and ultrasound (grey scale, Doppler, elastography), optical coherence tomography (OCT) and nailfold capillaroscopy techniques with experienced practitioners and state-of-the-art equipment. We have experience in semi-quantitative and (through collaborators Imorphics) quantitative assessment of imaging pathologies.

We support educational and training initiatives for imaging, in particular for ultrasound at both undergraduate and postgraduate levels.

Funding

Key publications

  1. .
    Emery P, Burmester GR, Naredo E, Zhou Y, Hojnik M, Conaghan PG.
    BMJ ÂÌñ»»ÆÞ. 2018 Feb 28;8(2):e019007. doi: 10.1136/bmjopen-2017-019007.
     
  2. .
    Dube B, Bowes MA, Hensor EMA, Barr A, Kingsbury SR, Conaghan PG.
    Osteoarthritis Cartilage. 2018 Oct;26(10):1333-1337. doi: 10.1016/j.joca.2018.06.011. Epub 2018 Jul 12.
     
  3. .
    Tran G, Cowling P, Smith T, Bury J, Lucas A, Barr A, Kingsbury SR, Conaghan PG.
    Arthritis Care Res (Hoboken). 2018 Aug;70(8):1169-1184. doi: 10.1002/acr.23554. Epub 2018 Jun.
     
  4. .
    Dube B, Bowes MA, Kingsbury SR, Hensor EMA, Muzumdar S, Conaghan PG.
    Osteoarthritis Cartilage. 2018 Jan;26(1):62-71. doi: 10.1016/j.joca.2017.10.012. Epub 2017 Oct 17.
     
  5. .
    Abignano G, Laws P, Del Galdo F, Marzo-Ortega H, McGonagle D.
    Clin Exp Dermatol. 2018 Sep 23. doi: 10.1111/ced.13786. [Epub ahead of print] No abstract available.
     
  6. .
    Tinazzi I, McGonagle D, Aydin SZ, Chessa D, Marchetta A, Macchioni P.
    Ann Rheum Dis. 2018 Jun;77(6):922-925. doi: 10.1136/annrheumdis-2017-212681. Epub 2018 Mar 6.
     
  7. .
    Mackie SL, Pease CT, Fukuba E, Harris E, Emery P, Hodgson R, Freeston J, McGonagle D.
    Ann Rheum Dis. 2015 Dec;74(12):2188-92. doi: 10.1136/annrheumdis-2015-207395. Epub 2015 Sep 16.
     
  8. .
    Baker JF, Østergaard M, Emery P, Baker DG, Conaghan PG.
    Clin Exp Rheumatol. 2017 Jul-Aug;35(4):607-613. Epub 2017 Jan 27.
     
  9. Responsiveness of clinical and ultrasound outcome measures in musculoskeletal systemic lupus erythematosus. Rheumatology.
    Mahmoud K, Zayat AS, Yusof Y, Hensor E, Conaghan PG, Emery P, Vital EM.
    In press
     

  10. Mandl P, Navarro-Compán V, Terslev L, Aegerter P, van der Heijde D, D'Agostino MA, Baraliakos X, Pedersen SJ, Jurik AG, Naredo E, Schueller-Weidekamm C, Weber U, Wick MC, Bakker PA, Filippucci E, Conaghan PG, Rudwaleit M, Schett G, Sieper J, Tarp S, Marzo-Ortega H, Østergaard M; European League Against Rheumatism (EULAR).
    Ann Rheum Dis. 2015 Jul;74(7):1327-39. doi: 10.1136/annrheumdis-2014-206971. Epub 2015 Apr 2.

 

Who we are

People

View our team members